The development and integration of data-driven approaches to improve and facilitate decision making are key priorities in chemical and pharmaceutical companies. In this symposium we focus on the exploitation of synthesis data, and on the advances in the analysis and design of new materials and active ingredients. Both areas achieved significant breakthroughs in the most recent years. Achieving a wide adoption of novel data driven approaches in the companies beyond the integration is the ultimate goal but not an easy task to undertake. Successful examples from industry will be presented to overcome this challenge.